HTRA1 抗体
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- 抗原 See all HTRA1 抗体
- HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HTRA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- HtrA serine peptidase 1
- 亚型
- IgG
- Top Product
- Discover our top product HTRA1 Primary Antibody
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anti-HtrA Serine Peptidase 1 (HTRA1) (AA 116-147), (N-Term) antibody
HTRA1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB02326 unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 23-248) antibodyHTRA1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) antibodyHTRA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 381-412), (C-Term) antibodyHTRA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB02327 unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 122-171) antibodyHTRA1 适用: 人, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 22-160) antibodyHTRA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (N-Term) antibodyHTRA1 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 389-419), (C-Term) antibodyHTRA1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
- 别名
- HTRA1 (HTRA1 产品)
- 别名
- htra1 antibody, zgc:92029 antibody, zgc:172061 antibody, l56 antibody, htra antibody, Xhtra1 antibody, prss11 antibody, MGC145723 antibody, ARMD7 antibody, CARASIL antibody, HtrA antibody, L56 antibody, ORF480 antibody, PRSS11 antibody, AI429470 antibody, HTRA antibody, Prss11 antibody, RSPP11 antibody, HTRA1 antibody, HtrA serine peptidase 1a antibody, HtrA serine peptidase 1 antibody, HtrA serine peptidase 1b antibody, Serine protease HTRA1 antibody, HtrA serine peptidase 1 S homeolog antibody, htra1a antibody, HTRA1 antibody, htra1b antibody, htra1 antibody, Htra1 antibody, htra1.S antibody
- 背景
- Synonyms:HTRA, PRSS11 Background:Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors(IGFs) by cleaving IGF-binding proteins. Inhibits signaling mediated by TGF-beta family members. This activity requires the integrity of the catalytic site, although it is unclear whether TGF-beta proteins are themselves degraded. By acting on TGF-beta signaling, may regulate many physiological processes, including retinal angiogenesis and neuronal survival and maturation during development. Intracellularly, degrades TSC2, leading to the activation of TSC2 downstream targets.
- 分子量
- 35 kDa, 50 kD, 42 kDa
- 基因ID
- 5654
- UniProt
- Q92743
- 途径
- Growth Factor Binding
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