LE antibody, 2010205O06Rik antibody, AU040608 antibody, BLOC-3 antibody, C130020P05Rik antibody, le antibody, mKIAA1667 antibody, HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 antibody, HPS4 antibody, Hps4 antibody
背景
Synonyms:KIAA1667 Background:Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor(GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38(PubMed:23084991).