Synonyms: Background:Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:9677400, PubMed:26416729). Channel characteristics depend on the subunit composition, heteropentameric channels display faster channel closure(By similarity). Plays an important role in the down-regulation of neuronal excitability(By similarity). Contributes to the generation of inhibitory postsynaptic currents(By similarity). Contributes to increased pain perception in response to increased prostaglandin E2 levels(By similarity). Plays a role in cellular responses to ethanol(By similarity).