Glutathione Peroxidase 2 抗体
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- 抗原 See all Glutathione Peroxidase 2 (GPX2) 抗体
- Glutathione Peroxidase 2 (GPX2)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Glutathione Peroxidase 2 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- Glutathione peroxidase 2
- 亚型
- IgG
- Top Product
- Discover our top product GPX2 Primary Antibody
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- 应用备注
- WB: 1:500-1:2000, IHC: 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- Glutathione Peroxidase 2 (GPX2)
- 别名
- GPX2 (GPX2 产品)
- 别名
- ATGPX2 antibody, GLUTATHIONE PEROXIDASE antibody, T9H9.9 antibody, T9H9_9 antibody, glutathione peroxidase 2 antibody, GI-GPx antibody, GPRP antibody, GPRP-2 antibody, GPx-2 antibody, GPx-GI antibody, GSHPX-GI antibody, GSHPx-2 antibody, LOC100136264 antibody, GSHPx-GI antibody, GPX-GI antibody, glutathione peroxidase 2 antibody, glutathione peroxidase 1 antibody, GPX2 antibody, gpx1 antibody, Gpx2 antibody, LELG_01052 antibody
- 背景
- Synonyms:GPX2, GI-GPx, GPRP, GPRP-2 Background:The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.
- 分子量
- 21 kDa
- UniProt
- P18283
- 途径
- Thyroid Hormone Synthesis
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