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GEMIN5 抗体

GEMIN5 适用: 人 WB, IP, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7114527
发货至: 中国
  • 抗原 See all GEMIN5 抗体
    GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
    适用
    • 5
    • 1
    宿主
    • 5
    克隆类型
    • 5
    多克隆
    标记
    • 5
    This GEMIN5 antibody is un-conjugated
    应用范围
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    gem(nuclear organelle) associated protein 5
    亚型
    IgG
    Top Product
    Discover our top product GEMIN5 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
    别名
    GEMIN5 (GEMIN5 产品)
    别名
    GEMIN-5 antibody, AA407055 antibody, AA407208 antibody, AI451603 antibody, BB194447 antibody, C330013N08 antibody, gem nuclear organelle associated protein 5 antibody, gem (nuclear organelle) associated protein 5 antibody, GEMIN5 antibody, Gemin5 antibody
    背景
    Synonyms: Background:The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. GEMIN5 acts as the snRNA-binding protein of the SMN complex.
    分子量
    168 kDa
    基因ID
    25929
    UniProt
    Q8TEQ6
    途径
    Ribonucleoprotein Complex Subunit Organization
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