FAF2 antibody, UBXD8 antibody, ETEA antibody, UBXN3B antibody, 2210404D11Rik antibody, AI462440 antibody, Ubxd8 antibody, mKIAA0887 antibody, 2210404d11rik antibody, RGD1306577 antibody, UBX8 antibody, etea antibody, ubxd8 antibody, ubxn3b antibody, Fas associated factor family member 2 antibody, Fas associated factor family member 2 S homeolog antibody, FAF2 antibody, Faf2 antibody, faf2.S antibody
背景
Synonyms:ETEA, KIAA0887, UBXD8, UBXN3B Background:Plays an important role in endoplasmic reticulum-associated degradation(ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins(PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis(PubMed:23297223).