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FAM20C 抗体

FAM20C 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7114089
发货至: 中国
  • 抗原 See all FAM20C 抗体
    FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))
    适用
    • 24
    • 20
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 39
    克隆类型
    • 39
    多克隆
    标记
    • 12
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAM20C antibody is un-conjugated
    应用范围
    • 35
    • 20
    • 14
    • 13
    • 13
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    family with sequence similarity 20, member C
    亚型
    IgG
    Top Product
    Discover our top product FAM20C Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))
    别名
    FAM20C (FAM20C 产品)
    别名
    DMP-4 antibody, DMP4 antibody, GEF-CK antibody, RNS antibody, C76981 antibody, mKIAA4081 antibody, RGD1311980 antibody, si:ch73-266a4.1 antibody, FAM20C, golgi associated secretory pathway kinase antibody, family with sequence similarity 20, member C antibody, family with sequence similarity 20, member Cb antibody, FAM20C antibody, Fam20c antibody, fam20cb antibody
    背景
    Synonyms:Dentin matrix protein 4, DMP 4, DMP4, FAM20C, Protein FAM20C, RNS Background:Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth(PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome(PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity(PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1(PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion(PubMed:26091039).
    分子量
    50 kDa
    基因ID
    56975
    UniProt
    Q8IXL6
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