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EYA2 抗体

EYA2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7114029
发货至: 中国
  • 抗原 See all EYA2 抗体
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    适用
    • 41
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 53
    • 3
    克隆类型
    • 54
    • 2
    多克隆
    标记
    • 20
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This EYA2 antibody is un-conjugated
    应用范围
    • 43
    • 25
    • 13
    • 13
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    eyes absent homolog 2(Drosophila)
    亚型
    IgG
    Top Product
    Discover our top product EYA2 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    别名
    EYA2 (EYA2 产品)
    别名
    EYA2 antibody, zgc:92279 antibody, eab1 antibody, Eab1 antibody, EAB1 antibody, EYA transcriptional coactivator and phosphatase 2 antibody, EYA2 antibody, eya2 antibody, Eya2 antibody
    背景
    Synonyms:EAB1 Background:Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5(PubMed:12500905, PubMed:23435380). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX(H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress(PubMed:19351884). Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2, in this it is functionally redundant with EYA1(PubMed:12500905).
    分子量
    57 kDa
    基因ID
    2139
    UniProt
    O00167
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