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eIF4EBP2 抗体

EIF4EBP2 适用: 人, 小鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7113973
发货至: 中国
  • 抗原 See all eIF4EBP2 (EIF4EBP2) 抗体
    eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))
    适用
    • 53
    • 6
    • 4
    • 4
    • 4
    • 4
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    • 1
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    人, 小鼠
    宿主
    • 50
    • 3
    克隆类型
    • 51
    • 2
    多克隆
    标记
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    This eIF4EBP2 antibody is un-conjugated
    应用范围
    • 27
    • 27
    • 13
    • 13
    • 9
    • 6
    • 3
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    eukaryotic translation initiation factor 4E binding protein 2
    亚型
    IgG
    Top Product
    Discover our top product EIF4EBP2 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))
    别名
    EIF4EBP2 (EIF4EBP2 产品)
    别名
    4ebp2 antibody, MGC75579 antibody, wu:fa55e11 antibody, wu:fp45e09 antibody, MGC78987 antibody, EIF4EBP2 antibody, eIF-4E antibody, Tb06.28P18.1010 antibody, 4EBP2 antibody, PHASII antibody, 2810011I19Rik antibody, 4E-BP2 antibody, AA792569 antibody, BC010348 antibody, PHAS-II antibody, eukaryotic translation initiation factor 4E binding protein 2 antibody, eukaryotic translation initiation factor 4E binding protein 2 L homeolog antibody, eukaryotic initiation factor 4E antibody, eukaryotic translation initiation factor 4E antibody, putative eukaryotic translation initiation factor 4e antibody, eif4ebp2 antibody, Eif4ebp2 antibody, eif4ebp2.L antibody, EIF4EBP2 antibody, eIF-4E antibody, Tb927.6.1870 antibody, LMJF_30_0450 antibody
    背景
    Synonyms: Background:Repressor of translation initiation involved in synaptic plasticity, learning and memory formation(By similarity). Regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form of EIF4EBP2 competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation(PubMed:25533957). EIF4EBP2 is enriched in brain and acts as a regulator of synapse activity and neuronal stem cell renewal via its ability to repress translation initiation(By similarity). Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways(By similarity).
    分子量
    ~20 kDa
    基因ID
    1979
    UniProt
    Q13542
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