Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) 抗体
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- 抗原 See all Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) 抗体
- Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 纯化方法
- Protein A+G purification
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- eukaryotic translation initiation factor 3, subunit M
- 克隆位点
- 1A4
- 亚型
- IgG1
- Top Product
- Discover our top product EIF3M Primary Antibody
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- 应用备注
- WB: 1:500-1:2000, IF: 1:10-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)
- 别名
- EIF3M (EIF3M 产品)
- 物质类
- Viral Protein
- 背景
- Synonyms:HFLB5, PCID1 Background:Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1(HSV1) or herpes simplex virus 2(HSV2).
- 分子量
- 43 kDa
- 基因ID
- 10480
- UniProt
- Q7L2H7
- 途径
- Ribonucleoprotein Complex Subunit Organization
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