C20orf31 antibody, C20orf49 antibody, bA4204.1 antibody, 9530090G24Rik antibody, AI327354 antibody, RGD1303074 antibody, MGC88910 antibody, DKFZp459A0314 antibody, ER degradation enhancing alpha-mannosidase like protein 2 antibody, ER degradation enhancer, mannosidase alpha-like 2 antibody, EDEM2 antibody, Edem2 antibody, edem2 antibody
背景
Synonyms:C20orf31, C20orf49 Background:Initiates the endoplasmic reticulum-associated degradation(ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2(PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.