elovl4 antibody, MGC122553 antibody, ADMD antibody, CT118 antibody, ISQMR antibody, STGD2 antibody, STGD3 antibody, elongation of very long chain fatty acids protein 4 antibody, ELOVL fatty acid elongase 4 antibody, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 antibody, CpipJ_CPIJ002114 antibody, CpipJ_CPIJ003687 antibody, CpipJ_CPIJ011025 antibody, CpipJ_CPIJ013819 antibody, ELOVL4 antibody, elovl4 antibody, Elovl4 antibody
背景
Synonyms: Background:Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long-and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.