ECD/SGT1 抗体
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- 抗原 See all ECD/SGT1 (ECD) 抗体
- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ECD/SGT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- ecdysoneless homolog(Drosophila)
- 亚型
- IgG
- Top Product
- Discover our top product ECD Primary Antibody
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anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibody
ECD 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-300) antibodyECD 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 1-644) antibodyECD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (C-Term) antibodyECD 适用: 人, 山羊, 马, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ecdysoneless Homolog (ECD) (AA 72-121) antibodyECD 适用: 人, 山羊, 马, 兔, Cow, Pig, 犬, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
- 别名
- ECD (ECD 产品)
- 别名
- GCR2 antibody, HSGT1 antibody, 5730461K03Rik antibody, Hsgt1 antibody, ecdysoneless cell cycle regulator antibody, ecdysoneless homolog (Drosophila) antibody, ECD antibody, Ecd antibody
- 背景
- Synonyms:ECD, GCR2, HSGT1, Protein ecdysoneless homolog, Protein SGT1, SGT1, Suppressor of GCR2 Background:Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP(PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes(PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins(PubMed:19640839). The cell cycle-regulating function may depend on its RUVBL1-mediated association with the R2TP complex(PubMed:26711270). May play a role in regulation of pre-mRNA splicing(PubMed:24722212).
- 分子量
- 70-100 kDa
- 基因ID
- 11319
- UniProt
- O95905
- 途径
- Regulation of Carbohydrate Metabolic Process
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