DNAJA1 antibody, dj-2 antibody, dja1 antibody, hdj-2 antibody, hdj2 antibody, hsdj antibody, hsj2 antibody, hspf4 antibody, nedd7 antibody, Hsj2 antibody, Nedd7 antibody, DJ-2 antibody, DjA1 antibody, HDJ2 antibody, HSDJ antibody, HSJ2 antibody, HSPF4 antibody, NEDD7 antibody, hDJ-2 antibody, dnaja1l antibody, dnj-12 antibody, wu:fc14c09 antibody, zgc:55650 antibody, dnaJ homolog subfamily A member 1 pseudogene antibody, DnaJ heat shock protein family (Hsp40) member A1 antibody, DnaJ heat shock protein family (Hsp40) member A1 L homeolog antibody, DnaJ (Hsp40) homolog, subfamily A, member 1 antibody, LOC703360 antibody, dnaja1 antibody, DNAJA1 antibody, dnaja1.L antibody, Dnaja1 antibody
背景
Synonyms:DJ 2, DjA1, DnaJ protein homolog 2, DNAJ2, DNAJA1, hDJ 2, HDJ2, Heat shock 40 kDa protein 4, Heat shock protein J2, HSDJ, HSJ 2, HSJ2, HSPF4, Human DnaJ protein 2 Background:Co-chaperone for HSPA8/Hsc70(PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A(in vitro)(PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis(PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV(PubMed:24512202).