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DOCK7 抗体

DOCK7 适用: 人, 大鼠, 小鼠 ELISA, WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7113381
发货至: 中国
  • 抗原 See all DOCK7 抗体
    DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
    适用
    • 35
    • 16
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 33
    • 2
    克隆类型
    • 35
    多克隆
    标记
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DOCK7 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    dedicator of cytokinesis 7
    亚型
    IgG
    Top Product
    Discover our top product DOCK7 Primary Antibody
  • 应用备注
    WB: 1:200-1:1000, IP: 1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))
    别名
    DOCK7 (DOCK7 产品)
    别名
    im:7145816 antibody, im:7157388 antibody, wu:fb93h07 antibody, ZIR2 antibody, 3110056M06Rik antibody, Gm430 antibody, m antibody, mKIAA1771 antibody, dedicator of cytokinesis 7 antibody, dedicator of cytokinesis protein 7 antibody, dedicator of cytokinesis 6 antibody, DOCK7 antibody, dock7 antibody, NAEGRDRAFT_56982 antibody, LOC100185115 antibody, dock6 antibody, Dock7 antibody
    背景
    Synonyms:dedicator of cytokinesis 7, DOCK7, KIAA1771, ZIR2 Background:Functions as a guanine nucleotide exchange factor(GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization(PubMed:16982419). Has a role in pigmentation(By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells(RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3(By similarity).Multiple isoforms of DOCK 7 exist due to alternative splicing events. This DOCK 7 antibody can recognize all the isoforms.
    分子量
    240 kDa
    基因ID
    85440
    UniProt
    Q96N67
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