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CHMP2A 抗体

CHMP2A 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112645
发货至: 中国
  • 抗原 See all CHMP2A 抗体
    CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 37
    • 2
    克隆类型
    • 39
    多克隆
    标记
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    This CHMP2A antibody is un-conjugated
    应用范围
    • 30
    • 13
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    • 8
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    • 2
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    chromatin modifying protein 2A
    亚型
    IgG
    Top Product
    Discover our top product CHMP2A Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    CHMP2A (Charged Multivesicular Body Protein 2A (CHMP2A))
    别名
    CHMP2A (CHMP2A 产品)
    别名
    BC-2 antibody, BC2 antibody, CHMP2 antibody, VPS2 antibody, VPS2A antibody, 1500016L11Rik antibody, RGD1305050 antibody, bc-2 antibody, bc2 antibody, chmp2 antibody, vps2 antibody, vps2a antibody, fj10d05 antibody, wu:fi18h03 antibody, wu:fj10d05 antibody, zgc:55361 antibody, charged multivesicular body protein 2a antibody, charged multivesicular body protein 2A antibody, Charged multivesicular body protein 2a antibody, charged multivesicular body protein 2A L homeolog antibody, ATEG_06167 antibody, LOC5570080 antibody, EDI_289610 antibody, PTRG_09933 antibody, NAEGRDRAFT_39042 antibody, PITG_17335 antibody, Tsp_00033 antibody, LOC100284170 antibody, LOC100284688 antibody, chm2a antibody, chmp2a antibody, CHMP2A antibody, Chmp2a antibody, chmp2a.L antibody
    背景
    Synonyms:BC2, CHMP2 Background:Probable core component of the endosomal sorting required for transport complex III(ESCRT-III) which is involved in multivesicular bodies(MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O,-I,-II and-III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis(PubMed:21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase(PubMed:26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. (Microbial infection) The ESCRT machinery functions in topologically equivalent membrane fission events, such as the budding of enveloped viruses(HIV-1 and other lentiviruses). Involved in HIV-1 p6-and p9-dependent virus release.
    分子量
    32 kDa
    基因ID
    27243
    UniProt
    O43633
    途径
    SARS-CoV-2 Protein Interactome
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