电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CEP152 抗体

CEP152 适用: 人, 小鼠 ELISA, WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112602
发货至: 中国
  • 抗原 See all CEP152 抗体
    CEP152 (Centrosomal Protein 152kDa (CEP152))
    适用
    人, 小鼠
    宿主
    • 15
    • 1
    克隆类型
    • 15
    • 1
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEP152 antibody is un-conjugated
    应用范围
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    centrosomal protein 152kDa
    亚型
    IgG
    Top Product
    Discover our top product CEP152 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    CEP152 (Centrosomal Protein 152kDa (CEP152))
    别名
    CEP152 (CEP152 产品)
    背景
    Synonyms:KIAA0912 Background:Necessary for centrosome duplication, the function seems also to involve CEP63, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication(PubMed:26297806). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 Molecules involved in centriole formation(PubMed:21059844, PubMed:20852615). Proposed to snatch PLK4 away from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 at the outer boundary of a newly forming CEP152 ring structure(PubMed:24997597). Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles(By similarity). Overexpression of CEP152 can drive amplification of centrioles(PubMed:20852615).
    分子量
    110 kDa
    基因ID
    22995
    UniProt
    O94986
    途径
    M Phase
You are here:
客服