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CDK5RAP3 抗体

CDK5RAP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112544
发货至: 中国
  • 抗原 See all CDK5RAP3 抗体
    CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
    适用
    • 49
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    人, 小鼠, 大鼠
    宿主
    • 47
    • 2
    克隆类型
    • 47
    • 2
    多克隆
    标记
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    This CDK5RAP3 antibody is un-conjugated
    应用范围
    • 33
    • 14
    • 13
    • 13
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    CDK5 regulatory subunit associated protein 3
    亚型
    IgG
    Top Product
    Discover our top product CDK5RAP3 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
    别名
    CDK5RAP3 (CDK5RAP3 产品)
    别名
    cdkrap3 antibody, fb33h04 antibody, fc09c05 antibody, id:ibd2920 antibody, wu:fb33h04 antibody, wu:fc09c05 antibody, zgc:86863 antibody, CDK5RAP3 antibody, cdk5rap3 antibody, MGC82350 antibody, C53 antibody, HSF-27 antibody, IC53 antibody, LZAP antibody, MST016 antibody, OK/SW-cl.114 antibody, PP1553 antibody, 1810007E24Rik antibody, BC002318 antibody, C81486 antibody, CDK5 regulatory subunit associated protein 3 antibody, CDK5 regulatory subunit associated protein 3 L homeolog antibody, cdk5rap3 antibody, CDK5RAP3 antibody, cdk5rap3.L antibody, Cdk5rap3 antibody
    背景
    Synonyms:IC53, Background:Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation(PubMed:12054757, PubMed:12737517). Negatively regulates NF-kappa-B-mediated gene transcription through the control of RELA phosphorylation(PubMed:17785205, PubMed:20228063). Also regulates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint(PubMed:15790566, PubMed:19223857). Through its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation(PubMed:16173922). May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress(PubMed:23152784). May also play a role in the rupture of the nuclear envelope during apoptosis(PubMed:23478299). May regulate MAPK14 activity by regulating its dephosphorylation by PPM1D/WIP1(PubMed:21283629). (Microbial infection) May be negatively regulated by hepatitis B virus large envelope protein mutant pre-s2 to promote mitotic entry.
    分子量
    65 kDa
    基因ID
    80279
    UniProt
    Q96JB5
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