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CNOT3 抗体

CNOT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112435
发货至: 中国
  • 抗原 See all CNOT3 抗体
    CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))
    适用
    • 33
    • 10
    • 10
    • 10
    • 8
    • 8
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 30
    • 3
    克隆类型
    • 30
    • 3
    多克隆
    标记
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    This CNOT3 antibody is un-conjugated
    应用范围
    • 27
    • 16
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    CCR4-NOT transcription complex, subunit 3
    亚型
    IgG
    Top Product
    Discover our top product CNOT3 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))
    别名
    CNOT3 (CNOT3 产品)
    背景
    Synonyms:KIAA0691, LENG2, NOT3 Background:Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation, may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem(ES) cell identity.
    分子量
    120 kDa
    基因ID
    4849
    UniProt
    O75175
    途径
    Stem Cell Maintenance
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