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Calsyntenin 1 抗体

CLSTN1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112234
发货至: 中国
  • 抗原 See all Calsyntenin 1 (CLSTN1) 抗体
    Calsyntenin 1 (CLSTN1)
    适用
    • 44
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 44
    克隆类型
    • 42
    • 2
    多克隆
    标记
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    This Calsyntenin 1 antibody is un-conjugated
    应用范围
    • 38
    • 17
    • 13
    • 13
    • 6
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    calsyntenin 1
    亚型
    IgG
    Top Product
    Discover our top product CLSTN1 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    Calsyntenin 1 (CLSTN1)
    别名
    CLSTN1 (CLSTN1 产品)
    别名
    CALSYNTENIN-1 antibody, fm67g03 antibody, wu:fk52g02 antibody, wu:fm67g03 antibody, zgc:153744 antibody, zgc:56528 antibody, clstn1 antibody, 1810034E21Rik antibody, Cst-1 antibody, Cstn1 antibody, ALC-ALPHA antibody, CDHR12 antibody, CSTN1 antibody, PIK3CD antibody, XB31alpha antibody, alcalpha1 antibody, alcalpha2 antibody, calsyntenin 1 antibody, calsyntenin 3 antibody, beta-catenin-interacting protein 1 antibody, calsyntenin-1 antibody, CLSTN1 antibody, clstn1 antibody, clstn3 antibody, LOC100356725 antibody, LOC100435584 antibody, Clstn1 antibody, LOC479600 antibody
    背景
    Synonyms:CS1, KIAA0911 Background:Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment(AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals(By similarity).
    分子量
    109kd
    基因ID
    22883
    UniProt
    O94985
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