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BRD7 抗体

BRD7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7112077
发货至: 中国
  • 抗原 See all BRD7 抗体
    BRD7 (Bromodomain Containing 7 (BRD7))
    适用
    • 43
    • 33
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 50
    • 1
    克隆类型
    • 49
    • 2
    多克隆
    标记
    • 17
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    • 1
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    This BRD7 antibody is un-conjugated
    应用范围
    • 25
    • 20
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    bromodomain containing 7
    亚型
    IgG
    Top Product
    Discover our top product BRD7 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    BRD7 (Bromodomain Containing 7 (BRD7))
    别名
    BRD7 (BRD7 产品)
    别名
    zgc:66347 antibody, wu:fc95f02 antibody, MGC79478 antibody, BRD7 antibody, BP75 antibody, CELTIX1 antibody, NAG4 antibody, Ptpn13ip antibody, bromodomain containing 7 L homeolog antibody, bromodomain containing 7 antibody, brd7.L antibody, brd7 antibody, BRD7 antibody, Brd7 antibody
    背景
    Synonyms:BP75, CELTIX1 Background:Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR(By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9'(H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.
    分子量
    70-74kd
    基因ID
    29117
    UniProt
    Q9NPI1
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