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BEX2 抗体

This anti-BEX2 antibody is a 兔 多克隆 antibody detecting BEX2 in ELISA, IHC 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7112040
发货至: 中国

Quick Overview for BEX2 抗体 (ABIN7112040)

抗原

See all BEX2 抗体
BEX2 (Brain Expressed X-Linked 2 (BEX2))

适用

人, 小鼠, 大鼠

宿主

  • 14

克隆类型

  • 14
多克隆

标记

  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BEX2 antibody is un-conjugated

应用范围

  • 6
  • 3
  • 2
  • 1
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
  • 纯化方法

    Immunogen affinity purified

    纯度

    ≥95 % as determined by SDS-PAGE

    免疫原

    brain expressed X-linked 2

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:1000, IHC: 1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    有效期

    12 months
  • 抗原

    BEX2 (Brain Expressed X-Linked 2 (BEX2))

    别名

    BEX2

    背景

    Synonyms:BEX1, BEX1/2, BEX2, brain expressed X linked 2, hBex2, Protein BEX2 Background:Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94 % . This antibody detects both BEX1 and BEX2.

    分子量

    10-15 kDa

    基因ID

    84707

    UniProt

    Q9BXY8
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