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ANKRD15 抗体

ANKRD15 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7111596
发货至: 中国
  • 抗原 See all ANKRD15 抗体
    ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))
    适用
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 10
    • 3
    克隆类型
    • 10
    • 3
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    This ANKRD15 antibody is un-conjugated
    应用范围
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    KN motif and ankyrin repeat domains 1
    亚型
    IgG
    Top Product
    Discover our top product ANKRD15 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))
    别名
    KANK1 (ANKRD15 产品)
    别名
    ANKRD15 antibody, CPSQ2 antibody, KANK antibody, A930031B09Rik antibody, AU015049 antibody, AW121052 antibody, Ankrd15 antibody, D330024H06Rik antibody, mKIAA0172 antibody, KANK1 antibody, ankrd15 antibody, kank1.2 antibody, DMRT1 antibody, KN motif and ankyrin repeat domains 1 antibody, KN motif and ankyrin repeat domains 1 L homeolog antibody, doublesex and mab-3 related transcription factor 1 antibody, KANK1 antibody, Kank1 antibody, kank1.L antibody, DMRT1 antibody
    背景
    Synonyms:ANKRD15, KANK, KIAA0172 Background:Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity, the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia, the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading, the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.
    分子量
    75-85kd,30kd
    基因ID
    23189
    UniProt
    Q14678
    途径
    Regulation of Actin Filament Polymerization
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