Aminoacylase 1 抗体
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- 抗原 See all Aminoacylase 1 (ACY1) 抗体
- Aminoacylase 1 (ACY1)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Aminoacylase 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- aminoacylase 1
- 亚型
- IgG
- Top Product
- Discover our top product ACY1 Primary Antibody
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- 应用备注
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- Aminoacylase 1 (ACY1)
- 别名
- Aminoacylase 1 (ACY1 产品)
- 别名
- si:zfos-226g1.1 antibody, zgc:55605 antibody, zgc:76955 antibody, acy1 antibody, acy1d antibody, acylase antibody, ACY1 antibody, ACY-1 antibody, ACY1D antibody, 1110014J22Rik antibody, Acy-1 antibody, Acy1a antibody, Acy1b antibody, aminoacylase 1 antibody, aminoacylase 1, gene 1 S homeolog antibody, aminoacylase 1, gene 1 antibody, ACY1 antibody, acy1 antibody, acy1.1.S antibody, acy1.1 antibody, Acy1 antibody
- 背景
- Synonyms:ACY 1, ACY1, ACY1D, ACYLASE, Aminoacylase 1 Background:This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.
- 分子量
- 46 kDa
- 基因ID
- 95
- UniProt
- Q03154
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