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alpha Actinin 抗体

ACTN 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7111505
发货至: 中国
  • 抗原 See all alpha Actinin (ACTN) 抗体
    alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
    适用
    人, 小鼠, 大鼠, 猴
    宿主
    • 9
    • 2
    克隆类型
    • 9
    • 2
    多克隆
    标记
    • 7
    • 2
    • 2
    This alpha Actinin antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    actinin, alpha 1
    亚型
    IgG
    Top Product
    Discover our top product ACTN Primary Antibody
  • 应用备注
    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
    别名
    alpha Actinin (ACTN 产品)
    别名
    actinin, alpha 4 antibody, alpha-actinin antibody, ACTN4 antibody, ain1 antibody
    背景
    Synonyms:actinin, alpha 1, ACTN1, alpha Actinin, Alpha actinin 1, F actin cross linking protein, Non muscle alpha actinin 1 Background:Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
    分子量
    110 kDa
    基因ID
    87
    UniProt
    P12814
    途径
    Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
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