JAML 抗体
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- 抗原 See all JAML (AMICA1) 抗体
- JAML (AMICA1) (Adhesion Molecule, Interacts with CXADR Antigen 1 (AMICA1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JAML antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- adhesion molecule, interacts with CXADR antigen 1
- 亚型
- IgG
- Top Product
- Discover our top product AMICA1 Primary Antibody
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anti-Adhesion Molecule, Interacts with CXADR Antigen 1 (AMICA1) (C-Term) antibody
AMICA1 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adhesion Molecule, Interacts with CXADR Antigen 1 (AMICA1) (AA 1-355) antibodyAMICA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Adhesion Molecule, Interacts with CXADR Antigen 1 (AMICA1) antibodyAMICA1 适用: 小鼠 FACS, IP 宿主: 仓鼠 Monoclonal 4E10 unconjugated
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- 应用备注
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- JAML (AMICA1) (Adhesion Molecule, Interacts with CXADR Antigen 1 (AMICA1))
- 别名
- JAML (AMICA1 产品)
- 别名
- RGD1562572 antibody, AMICA antibody, CREA7-1 antibody, CREA7-4 antibody, Gm638 antibody, JAML antibody, Crea7 antibody, junction adhesion molecule like antibody, Jaml antibody, JAML antibody
- 背景
- Synonyms:AMICA1 Background:Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.
- 分子量
- 30kd,44kd,50-60kd
- 基因ID
- 120425
- UniProt
- Q86YT9
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