AKAP8L 抗体
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- 抗原 See all AKAP8L 抗体
- AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AKAP8L antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 纯化方法
- Immunogen affinity purified
- 纯度
- ≥95 % as determined by SDS-PAGE
- 免疫原
- A kinase(PRKA) anchor protein 8-like
- 亚型
- IgG
- Top Product
- Discover our top product AKAP8L Primary Antibody
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anti-A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L) (C-Term) antibody
AKAP8L 适用: 人, 大鼠, 犬, 马, Cow, 兔, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L) (AA 1-240) antibodyAKAP8L 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L) (C-Term) antibodyAKAP8L 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Pig, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L) (AA 351-400) antibodyAKAP8L 适用: 人, 大鼠, 犬, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L) (AA 485-512), (C-Term) antibodyAKAP8L 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB36906 unconjugated
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- 应用备注
- WB: 1:200-1:2000, IF: 1:20-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- 有效期
- 12 months
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- 抗原
- AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))
- 别名
- AKAP8L (AKAP8L 产品)
- 别名
- HA95 antibody, HAP95 antibody, NAKAP antibody, NAKAP95 antibody, Nakap95 antibody, zgc:85966 antibody, AKAP8L antibody, A-kinase anchoring protein 8 like antibody, A kinase (PRKA) anchor protein 8-like antibody, A-kinase anchoring protein 8 like L homeolog antibody, AKAP8L antibody, Akap8l antibody, akap8l antibody, akap8l.L antibody
- 背景
- Synonyms:A kinase anchor protein 8 like, AKAP8 like protein, AKAP8L, DKFZp434L0650, HA95, HAP95, Helicase A binding protein 95, Homologous to AKAP95 protein, NAKAP, NAKAP95, Neighbor of AKAP95 Background:Could play a role in constitutive transport element(CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export(PubMed:10748171, PubMed:11402034). Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA(PubMed:10761695, PubMed:11884601). May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis(PubMed:11034899). May regulate the initiation phase of DNA replication when associated with TMPO isoform Beta(PubMed:12538639). Required for cell cycle G2/M transition and histone deacetylation during mitosis. In mitotic cells recruits HDAC3 to the vicinity of chromatin leading to deacetylation and subsequent phosphorylation at 'Ser-10' of histone H3, in this function seems to act redundantly with AKAP8(PubMed:16980585). May be involved in regulation of pre-mRNA splicing(PubMed:17594903). (Microbial infection) In case of EBV infection, may target PRKACA to EBNA-LP-containing nuclear sites to modulate transcription from specific promoters(PubMed:11884601). Can synergize with DHX9 to activate the CTE-mediated gene expression of type D retroviruses(PubMed:11402034). In case of HIV-1 infection, involved in the DHX9-promoted annealing of host tRNA(Lys3) to viral genomic RNA as a primer in reverse transcription, in vitro negatively regulates DHX9 annealing activity(PubMed:25034436).
- 分子量
- 72 kDa
- 基因ID
- 26993
- UniProt
- Q9ULX6
- 途径
- SARS-CoV-2 Protein Interactome
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