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OAS2 抗体

OAS2 适用: 人, 小鼠 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7111098
发货至: 中国
  • 抗原 See all OAS2 抗体
    OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
    适用
    • 30
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 23
    • 6
    • 2
    克隆类型
    • 25
    • 6
    多克隆
    标记
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OAS2 antibody is un-conjugated
    应用范围
    • 18
    • 12
    • 11
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    2'-5'-oligoadenylate synthetase 2, 69/71kDa
    亚型
    IgG
    Top Product
    Discover our top product OAS2 Primary Antibody
  • 应用备注
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
    别名
    OAS2 (OAS2 产品)
    别名
    Oasl11 antibody, 2'-5'-oligoadenylate synthetase 2 antibody, 2'-5' oligoadenylate synthetase 2 antibody, 2'-5'-oligoadenylate synthetase 2, 69/71kDa antibody, OAS2 antibody, Oas2 antibody
    背景
    Synonyms: Background:Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates(2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L(RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L.
    分子量
    66-71kd
    基因ID
    4939
    UniProt
    P29728
    途径
    Hepatitis C
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