MACC1 抗体 (AA 761-852)
(6 references)-
- 抗原 See all MACC1 抗体
- MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))
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抗原表位
- AA 761-852
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MACC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Cow
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MACC1
- 亚型
- IgG
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anti-Metastasis Associated in Colon Cancer 1 (MACC1) (AA 371-514) antibody
MACC1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated in Colon Cancer 1 (MACC1) (AA 522-784) antibodyMACC1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated in Colon Cancer 1 (MACC1) (AA 522-784) antibodyMACC1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D4 unconjugated
anti-Metastasis Associated in Colon Cancer 1 (MACC1) (Center) antibodyMACC1 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "MACC‑1 antibody target therapy suppresses growth and migration of non‑small cell lung cancer." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 7329-7336, (2017) (PubMed).
: "Loss of zfp36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of zeb1, sox9 and macc1." in: Oncotarget, Vol. 7, Issue 37, pp. 59144-59157, (2016) (PubMed).
: "Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 3423-31, (2015) (PubMed).
: "Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer." in: Oncology letters, Vol. 9, Issue 5, pp. 1989-1996, (2015) (PubMed).
: "Expression of MACC1 and c-Met in human gastric cancer and its clinical significance." in: Cancer cell international, Vol. 13, Issue 1, pp. 121, (2013) (PubMed).
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: "MACC‑1 antibody target therapy suppresses growth and migration of non‑small cell lung cancer." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 7329-7336, (2017) (PubMed).
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- 抗原
- MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))
- 别名
- MACC1 (MACC1 产品)
- 别名
- 7A5 antibody, SH3BP4L antibody, 4732474O15Rik antibody, Gm267 antibody, 7a5 antibody, RGD1309838 antibody, MACC1, MET transcriptional regulator antibody, metastasis associated in colon cancer 1 antibody, MACC1 antibody, Macc1 antibody
- 背景
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Synonyms: 7A5, SH3BP4L, Metastasis-associated in colon cancer protein 1, SH3 domain-containing protein 7a5, MACC1
Background: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.
- 基因ID
- 346389
- UniProt
- Q6ZN28
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