BARD1 抗体 (AA 101-200)
(1 reference)-
- 抗原 See all BARD1 抗体
- BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
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抗原表位
- AA 101-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BARD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BARD1
- 亚型
- IgG
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anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 658-757) antibody
BARD1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (N-Term) antibodyBARD1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (N-Term) antibodyBARD1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) (AA 428-777) antibodyBARD1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) antibodyBARD1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-BRCA1 Associated RING Domain 1 (BARD1) antibodyBARD1 适用: 人 WB, IP, DB 宿主: 小鼠 Monoclonal 2059C4a unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "FOXK2 transcription factor suppresses ER?-positive breast cancer cell growth through down-regulating the stability of ER? via mechanism involving BRCA1/BARD1." in: Scientific reports, Vol. 5, pp. 8796, (2015) (PubMed).
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: "FOXK2 transcription factor suppresses ER?-positive breast cancer cell growth through down-regulating the stability of ER? via mechanism involving BRCA1/BARD1." in: Scientific reports, Vol. 5, pp. 8796, (2015) (PubMed).
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- 抗原
- BARD1 (BRCA1 Associated RING Domain 1 (BARD1))
- 别名
- BARD1 (BARD1 产品)
- 别名
- BARD1 antibody, LOC100147913 antibody, ENSMUSG00000060893 antibody, ENSMUSG00000073653 antibody, BRCA1 associated RING domain 1 antibody, BARD1 antibody, bard1 antibody, Bard1 antibody
- 背景
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Synonyms: BRCA1-associated RING domain protein 1, BARD-1, BARD1
Background: Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.
- 基因ID
- 580
- UniProt
- Q99728
- 途径
- DNA Damage Repair
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