PKD2 抗体 (AA 41-140)
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- 抗原 See all PKD2 抗体
- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
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抗原表位
- AA 41-140
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PKD2 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Cow,Pig,Horse,Rabbit,Zebrafish
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Polycystin 2
- 亚型
- IgG
- Top Product
- Discover our top product PKD2 Primary Antibody
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anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 261-360) antibody
PKD2 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 680-968) antibodyPKD2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (pSer876) antibodyPKD2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 261-360) antibodyPKD2 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 240-410) antibodyPKD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 651-750) antibodyPKD2 适用: 人, 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (Tyr654) antibodyPKD2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (C-Term) antibodyPKD2 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (Internal Region) antibodyVerified PKD2 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2) (AA 937-968), (C-Term) antibodyPKD2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1352 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000 - 限制
- 仅限研究用
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- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
- 别名
- Polycystin 2 (PKD2 产品)
- 别名
- APKD2 antibody, PC2 antibody, PKD4 antibody, Pc-2 antibody, TRPP2 antibody, C030034P18Rik antibody, RGD1559992 antibody, pkd2 antibody, trpp2 antibody, Cup antibody, PKD2L1 antibody, polycystin 2, transient receptor potential cation channel antibody, polycystic kidney disease 2 antibody, Polycystin-2 antibody, polycystin 2, transient receptor potential cation channel L homeolog antibody, PKD2 antibody, Pkd2 antibody, pkd-2 antibody, pkd2.L antibody, pkd2 antibody
- 背景
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Synonyms: polycystic kidney disease 2, TRPP2, APKD2, C030034P18RIK, MGC138466, MGC138468, PC2, PKD2 (includes EG:5311), PKD4, POLYCISTIN-2, POLYCYSTIN 2, RGD1559992, TRPP2, Polycystic kidney disease 2 protein homolog, PC2.
Background: Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Functions as a calcium permeable cation channel.
- 基因ID
- 5311
- UniProt
- Q13563
- 途径
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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