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PKD2 抗体 (AA 41-140) (Biotin)

PKD2 适用: 人 ELISA, WB 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7091533
发货至: 中国
  • 抗原 See all PKD2 抗体
    PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
    抗原表位
    • 15
    • 13
    • 11
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-140
    适用
    • 65
    • 54
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 72
    • 3
    • 1
    克隆类型
    • 74
    • 3
    多克隆
    标记
    • 41
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKD2 antibody is conjugated to Biotin
    应用范围
    • 42
    • 41
    • 13
    • 13
    • 11
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    交叉反应
    预测反应
    Mouse,Rat,Cow,Pig,Horse,Rabbit,Zebrafish
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Polycystin 2
    亚型
    IgG
    Top Product
    Discover our top product PKD2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
    别名
    Polycystin 2 (PKD2 产品)
    别名
    APKD2 antibody, PC2 antibody, PKD4 antibody, Pc-2 antibody, TRPP2 antibody, C030034P18Rik antibody, RGD1559992 antibody, pkd2 antibody, trpp2 antibody, Cup antibody, PKD2L1 antibody, polycystin 2, transient receptor potential cation channel antibody, polycystic kidney disease 2 antibody, Polycystin-2 antibody, polycystin 2, transient receptor potential cation channel L homeolog antibody, PKD2 antibody, Pkd2 antibody, pkd-2 antibody, pkd2.L antibody, pkd2 antibody
    背景

    Synonyms: polycystic kidney disease 2, TRPP2, APKD2, C030034P18RIK, MGC138466, MGC138468, PC2, PKD2 (includes EG:5311), PKD4, POLYCISTIN-2, POLYCYSTIN 2, RGD1559992, TRPP2, Polycystic kidney disease 2 protein homolog, PC2.

    Background: Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Functions as a calcium permeable cation channel.

    基因ID
    5311
    UniProt
    Q13563
    途径
    cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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