MAGED1 抗体 (AA 50-200)
-
- 抗原 See all MAGED1 抗体
- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
-
抗原表位
- AA 50-200
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This MAGED1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 预测反应
- Human
- 免疫原
- KLH conjugated synthetic peptide derived from human MAGED1
- 克隆位点
- C5D3
- Top Product
- Discover our top product MAGED1 Primary Antibody
-
-
- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
-
- 浓度
- 0.5 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
- 别名
- MAGED1 (MAGED1 产品)
- 别名
- MAGED1 antibody, DLXIN-1 antibody, NRAGE antibody, 2810433C11Rik antibody, 5430405L04Rik antibody, DXBwg1492e antibody, Dlixin antibody, Dlxin-1 antibody, Dlxin1 antibody, MAGE-D1 antibody, mFLJ00163 antibody, Nrage antibody, MAGE family member D1 antibody, melanoma antigen family D, 1 antibody, melanoma antigen, family D, 1 antibody, MAGED1 antibody, Maged1 antibody
- 背景
-
Synonyms: DLXIN 1, MAGD1_HUMAN, MAGE D1 antigen, MAGE tumor antigen CCF, MAGE-D1 antigen, Melanoma antigen family D 1, Melanoma associated antigen D1, Melanoma-associated antigen D1, Neurotrophin receptor interacting MAGE homolog, Neurotrophin receptor-interacting MAGE homolog, NRAGE, PP2250.
Background: Involved in the apoptotic response after nerve growthfactor (NGF) binding in neuronal cells. Binds NGFR/p75NTR andantagonizes its association with NTRK1/TrkA, inhibits cell cycleprogression, and facilitates NGFR-mediated apoptosis. May act as aregulator of the function of DLX family members. May regulateTP53/p53 transcriptional activity and inhibit cell proliferation.Enhances TP53 phosphorylation and accumulation. May enhanceubiquitin ligase activity of RING-type zinc finger-containing E3ubiquitin-protein ligases. Proposed to act through recruitmentand/or stabilization of the Ubl-conjugating enzyme (E2) at theE3:substrate complex.
- 基因ID
- 9500
- UniProt
- Q9Y5V3
- 途径
- Neurotrophin Signaling Pathway
-