DDX4 抗体 (C-Term)
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- 抗原 See all DDX4 抗体
- DDX4 (DEAD Box Protein 4 (DDX4))
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抗原表位
- C-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DDX4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Cow,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DDX4 C-term
- 亚型
- IgG
- Top Product
- Discover our top product DDX4 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- DDX4 (DEAD Box Protein 4 (DDX4))
- 别名
- DDX4 (DDX4 产品)
- 别名
- VASA antibody, AV206478 antibody, Mvh antibody, RVLG antibody, vasa antibody, vlg1 antibody, DEAD-box helicase 4 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 antibody, DEAD-box helicase 4 L homeolog antibody, DDX4 antibody, Ddx4 antibody, ddx4.L antibody
- 背景
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Synonyms: DDX 4, DEAD (Asp Glu Ala Asp) box polypeptide 4, Dead box protein 4, Dead-box protein 4, MGC111074, MVH, Probable ATP dependent RNA helicase DDX4, VASA, VASA homolog, DDX4_HUMAN.
Background: ATP-dependent RNA helicase required during spermatogenesis (PubMed:10920202, PubMed:21034600). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (By similarity). Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (By similarity). Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs (By similarity).
- 基因ID
- 54514
- UniProt
- Q9NQI0
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