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DDX39B 抗体 (AA 1-100) (HRP)

DDX39B 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal HRP
产品编号 ABIN7091026
发货至: 中国
  • 抗原 See all DDX39B 抗体
    DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))
    抗原表位
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 31
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 26
    • 5
    克隆类型
    • 25
    • 6
    多克隆
    标记
    • 15
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DDX39B antibody is conjugated to HRP
    应用范围
    • 20
    • 16
    • 14
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Cow,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human UAP56
    亚型
    IgG
    Top Product
    Discover our top product DDX39B Primary Antibody
  • 应用备注
    WB 1:300-5000
    限制
    仅限研究用
  • 浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • 抗原
    DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))
    别名
    UAP56 (DDX39B 产品)
    别名
    BAT1 antibody, D6S81E antibody, UAP56 antibody, Bat1 antibody, Bat1a antibody, p47 antibody, 0610030D10Rik antibody, AI428441 antibody, Bat-1 antibody, D17H6S81E antibody, D17H6S81E-1 antibody, D6S81Eh antibody, bat1 antibody, zgc:63773 antibody, DExD-box helicase 39B antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B antibody, DDX39B antibody, Ddx39b antibody, ddx39b antibody
    背景

    Synonyms: 56 kDa U2AF65-associated protein, ATP-dependent RNA helicase p47, B(0,+)-type amino acid transporter 1, BAT1, Bat1a, DEAD box protein UAP56, Glycoprotein-associated amino acid transporter b0,+AT1, HLA-B-associated transcript 1 protein, HLA-B-associated transcript 1A, HLA-B-associated transcript-1, p47, Solute carrier family 7 member 9, Spliceosome RNA helicase BAT1, UAP56, 56 kDa U2AF65-associated protein, ATP-dependent RNA helicase p47, 0610030D10Rik, 4F2-LC6, AI428441, D17H6S81E, D17H6S81E-1, D6S81E, D6S81Eh, DDX39B, DX39B_HUMAN, Glycoprotein-associated amino acid transporter b0,+AT1, MGC127051, MGC19235, MGC38799, nuclear RNA helicase (DEAD family), OTTHUMP00000029229, OTTHUMP00000165889, OTTHUMP00000165890, Spliceosome RNA helicase DDX39B, U2AF65-associayed protein, 56-KD.

    Background: Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and ALYREF/THOC4. Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint. Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity. Even with the stimulation of RNA, the ATPase activity is weak. Can only hydrolyze ATP but not other NTPs. The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA. However, ssRNA stimulates the ATPase activity much more strongly than dsRNA. Can unwind 5' or 3' overhangs or blunt end RNA duplexes in vitro. The ATPase and helicase activities are not influenced by U2AF2 and ALYREF/THOC4.

    基因ID
    7919
    UniProt
    Q13838
    途径
    Ribonucleoprotein Complex Subunit Organization
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