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ROS1 抗体

ROS1 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal F7Y3 unconjugated
产品编号 ABIN7090797
发货至: 中国
  • 抗原 See all ROS1 抗体
    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
    适用
    • 44
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    • 4
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    • 2
    宿主
    • 50
    • 5
    • 1
    小鼠
    克隆类型
    • 50
    • 6
    单克隆
    标记
    • 24
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    This ROS1 antibody is un-conjugated
    应用范围
    • 35
    • 18
    • 14
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Human
    免疫原
    Recombinant human ROS1.
    克隆位点
    F7Y3
    Top Product
    Discover our top product ROS1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 浓度
    0.5 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
    别名
    ROS1 (ROS1 产品)
    别名
    MCF3 antibody, ROS antibody, c-ros-1 antibody, ROS1C antibody, Ros-1 antibody, c-ros antibody, ROS proto-oncogene 1, receptor tyrosine kinase antibody, ROS proto-oncogene 1 , receptor tyrosine kinase antibody, Ros1 proto-oncogene antibody, ROS1 antibody, Ros1 antibody
    背景

    Synonyms: ROS, ros protein, c ros, c-ros, c ros1, MCF3, Oncogene ROS, OTTHUMP00000040389, Proto oncogene c ros 1 protein, Proto oncogene tyrosine protein kinase ROS, Proto oncogene tyrosine protein kinase ROS precursor, Ros1, ROS1C, Transmembrane tyrosine specific protein kinase, v ros avian UR2 sarcoma virus oncogene homolog 1, v ros UR2 sarcoma virus oncogene homolog 1, ROS1_HUMAN, Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, Receptor tyrosine kinase c-ros oncogene 1, c-Ros receptor tyrosine kinase

    Background: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.

    基因ID
    6098
    UniProt
    P08922
    途径
    RTK signaling
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