ROS1 抗体
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- 抗原 See all ROS1 抗体
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ROS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Human
- 免疫原
- Recombinant human ROS1.
- 克隆位点
- F7Y3
- Top Product
- Discover our top product ROS1 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 浓度
- 0.5 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
- 别名
- ROS1 (ROS1 产品)
- 别名
- MCF3 antibody, ROS antibody, c-ros-1 antibody, ROS1C antibody, Ros-1 antibody, c-ros antibody, ROS proto-oncogene 1, receptor tyrosine kinase antibody, ROS proto-oncogene 1 , receptor tyrosine kinase antibody, Ros1 proto-oncogene antibody, ROS1 antibody, Ros1 antibody
- 背景
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Synonyms: ROS, ros protein, c ros, c-ros, c ros1, MCF3, Oncogene ROS, OTTHUMP00000040389, Proto oncogene c ros 1 protein, Proto oncogene tyrosine protein kinase ROS, Proto oncogene tyrosine protein kinase ROS precursor, Ros1, ROS1C, Transmembrane tyrosine specific protein kinase, v ros avian UR2 sarcoma virus oncogene homolog 1, v ros UR2 sarcoma virus oncogene homolog 1, ROS1_HUMAN, Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, Receptor tyrosine kinase c-ros oncogene 1, c-Ros receptor tyrosine kinase
Background: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
- 基因ID
- 6098
- UniProt
- P08922
- 途径
- RTK signaling
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