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TXN2 抗体 (AA 101-166) (Biotin)

TXN2 适用: 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN705973
发货至: 中国
  • 抗原 See all TXN2 抗体
    TXN2 (Thioredoxin 2 (TXN2))
    抗原表位
    • 14
    • 9
    • 8
    • 6
    • 3
    • 1
    AA 101-166
    适用
    • 37
    • 28
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    大鼠
    宿主
    • 51
    • 1
    克隆类型
    • 50
    • 2
    多克隆
    标记
    • 19
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXN2 antibody is conjugated to Biotin
    应用范围
    • 38
    • 14
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Thioredoxin 2
    亚型
    IgG
    Top Product
    Discover our top product TXN2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    TXN2 (Thioredoxin 2 (TXN2))
    别名
    Thioredoxin 2 (TXN2 产品)
    别名
    MT-TRX antibody, MTRX antibody, TRX2 antibody, 31884 antibody, CG31884 antibody, CG3864 antibody, DTrx-2 antibody, DmTrx-2 antibody, DmelTrx-2 antibody, Dmel\\CG31884 antibody, Trx antibody, anon-WO0118547.188 antibody, dmtrx-2 antibody, 2510006J11Rik antibody, AI788873 antibody, Trx2 antibody, zgc:77127 antibody, thioredoxin 2 antibody, thioredoxin-2 antibody, thiol reductase thioredoxin antibody, thioredoxin 2 L homeolog antibody, TXN2 antibody, Trx-2 antibody, LOC409451 antibody, VPA0972 antibody, VS_RS18125 antibody, VCD_000568 antibody, VEA_000083 antibody, trx2 antibody, Txn2 antibody, txn2 antibody, txn2.L antibody
    背景

    Synonyms: mitochondrial thioredoxin, MT-TRX, MTRX, thioredoxin 2 precursor, Thioredoxin mitochondrial, Thioredoxin2, TRX 2, TRX2, TXN 2, TXN2.

    Background: Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

    基因ID
    25828
    途径
    Cell RedoxHomeostasis
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