PDIA2 抗体 (AA 431-525)
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- 抗原 See all PDIA2 抗体
- PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))
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抗原表位
- AA 431-525
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDIA2 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PDIA2
- 亚型
- IgG
- Top Product
- Discover our top product PDIA2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- PDIA2 (Protein Disulfide Isomerase Family A, Member 2 (PDIA2))
- 别名
- PDIA2 (PDIA2 产品)
- 别名
- PDIA2 antibody, DKFZp468D2220 antibody, 1810041F13Rik antibody, AI661267 antibody, Pdip antibody, Pdipl antibody, PDA2 antibody, PDI antibody, PDIP antibody, PDIR antibody, protein disulfide isomerase family A member 2 antibody, protein disulfide isomerase associated 2 antibody, protein disulfide isomerase family A, member 2 antibody, PDIA2 antibody, Pdia2 antibody
- 背景
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Synonyms: Pancreatic protein disulfide isomerase, PDA2, PDI, PDIA2, PDIP, Protein disulfide isomerase A2, Protein disulfide isomerase, Protein disulfide isomerase family A member 2, PDIA2_HUMAN.
Background: The three dimensional structure of many extracellular proteins is stabilized by the formation of disulphide bonds. Studies suggest that a microsomal enzyme known as Protein Disulphide Isomerase (PDI) is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI, which catalyses disulphide interchange between thiols and protein dilsulphides, has also been referred to as thiol:protein-disulphide oxidoreductase and as glutathione:insulin transhydrogenase because of its role in reduction of disulphide bonds. The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the carboxy-terminus of PDI and other soluble endoplasmic reticulum (ER) resident proteins including the 78 and 94 kDa glucose regulated proteins (GRP78 and GRP94 respectively). The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
- 基因ID
- 64714
- 途径
- Maintenance of Protein Location, Cell RedoxHomeostasis, Unfolded Protein Response
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