(1 reference)-
- 抗原 See all TSC1 抗体
- TSC1 (Tuberous Sclerosis 1 (TSC1))
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抗原表位
- AA 131-230
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适用
- 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TSC1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 交叉反应
- 绵羊
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Hamartin
- 亚型
- IgG
- Top Product
- Discover our top product TSC1 Primary Antibody
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anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibody
TSC1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A2 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 550-650) antibodyTSC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (C-Term) antibodyTSC1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibodyTSC1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5A8 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) antibodyTSC1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibodyTSC1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (pSer505) antibodyTSC1 适用: 人, 小鼠, 绵羊 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 101-344) antibodyTSC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (Center) antibodyTSC1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibodyTSC1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB11648 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "DNA methylation Landscape of body size variation in sheep." in: Scientific reports, Vol. 5, pp. 13950, (2016) (PubMed).
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: "DNA methylation Landscape of body size variation in sheep." in: Scientific reports, Vol. 5, pp. 13950, (2016) (PubMed).
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- 抗原
- TSC1 (Tuberous Sclerosis 1 (TSC1))
- 别名
- Hamartin/TSC1 (TSC1 产品)
- 别名
- LAM antibody, TSC antibody, hamartin antibody, mKIAA0243 antibody, tsc1 antibody, wu:fc38b04 antibody, fa99f04 antibody, wu:fa99f04 antibody, zgc:63657 antibody, TSC complex subunit 1 antibody, tuberous sclerosis 1 antibody, TSC complex subunit 1b antibody, TSC complex subunit 1a antibody, TSC1 antibody, Tsc1 antibody, tsc1b antibody, tsc1 antibody, tsc1a antibody
- 背景
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Synonyms: LAM, TSC1, Tuberous sclerosis 1 protein, TSC1_HUMAN.
Background: Hamartin, or TSC1, is a suspected tumor suppressor implicated in the disease tuberous sclerosis 1. It is a negative regulator of cell division controlling the transition from G0/G1 to S phase, and it seems to act through the phosphatidylinositol 3 kinase/Akt pathway. TSC1 interacts with tuberin m(TSC2), which is thought to be a GAP (GTPase Activating Protein) for the Rap1 and Rab5 small G Proteins. The Hamartin/Tuberin complex has been shown to inhibit mTor. Hamartin has also been shown to interact with ERM (Ezrin-Radixin-Moesin) proteins and with F-actin, suggesting a role for TSC proteins in modulation of cell adhesion and morphology.
- 基因ID
- 7248
- UniProt
- Q92574
- 途径
- RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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