CD58 抗体 (iFluor™488)
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- 抗原 See all CD58 抗体
- CD58
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD58 antibody is conjugated to iFluor™488
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应用范围
- Flow Cytometry (FACS)
- 产品特性
- The clone TS2/9 recognizes a 45-70 kD cell surface protein, currently known as CD58. It is a member of the immunoglobulin superfamily previously known as lymphocyte function-associated antigen 3 (LFA-3). Both hematopoietic and non-hematopoietic cells including B and T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts express CD58. CD58 has two isoforms and is highly expressed on antigen specific memory T cells and as well as dendritic cells. The CD58 mediates cellular adhesion and participates in signal transduction when it binds to its ligand, the CD2 antigen. Cellular interactions regulated by the CD58/CD2 antigens are involved in the antigen-independent adhesion pathway and cytotoxic T lymphocyte (CTL) activity.
- 纯化方法
- Purified
- 纯度
- >95 %
- 质量等级
- GMP Grade
- 免疫原
- Human cytolytic T cells
- 克隆位点
- TS2-9
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD58 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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- 抗原
- CD58
- 别名
- CD58 (CD58 产品)
- 别名
- LFA-3 antibody, LFA3 antibody, ag3 antibody, CD58 molecule antibody, CD58 antibody
- 背景
- The clone TS2/9 recognizes a 45-70 kD cell surface protein, currently known as CD58. It is a member of the immunoglobulin superfamily previously known as lymphocyte function-associated antigen 3 (LFA-3). Both hematopoietic and non-hematopoietic cells including B and T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts express CD58. CD58 has two isoforms and is highly expressed on antigen specific memory T cells and as well as dendritic cells. The CD58 mediates cellular adhesion and participates in signal transduction when it binds to its ligand, the CD2 antigen. Cellular interactions regulated by the CD58/CD2 antigens are involved in the antigen-independent adhesion pathway and cytotoxic T lymphocyte (CTL) activity.
- 基因ID
- 965
- UniProt
- P19256
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