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ZNF746 抗体

ZNF746 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7076272
发货至: 中国
  • 抗原 See all ZNF746 抗体
    ZNF746 (Zinc Finger Protein 746 (ZNF746))
    适用
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 5
    • 1
    克隆类型
    • 5
    • 1
    多克隆
    标记
    • 6
    This ZNF746 antibody is un-conjugated
    应用范围
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse PARIS
  • 应用备注
    WB (H) 1:500-1:1000, IHC/IF (M,R) 1:1500-1:3000/1:1500-1:3000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    ZNF746 (Zinc Finger Protein 746 (ZNF746))
    别名
    PARIS (ZNF746 产品)
    别名
    PARIS antibody, 2810407L07Rik antibody, AI317225 antibody, Znf746 antibody, RGD1306209 antibody, zinc finger protein 746 antibody, ZNF746 antibody, Zfp746 antibody
    背景
    ZNF746, also named as PARIS, which belongs to the krueppel C2H2-type zinc-finger protein family. ZNF746 mainly localizes to the cytoplasm and probably translocates to the nucleus to repress selected genes. ZNF746 as a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. ZNF746 may act as a downstream effector of PRKN and contribute to neurodegeneration in Parkinson disease cases caused by defects in PRKN.
    分子量
    100 kDa
    基因ID
    69228
    NCBI登录号
    NP_001156947
    UniProt
    Q3U133
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