ube3a 抗体
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- 抗原 See all ube3a 抗体
- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ube3a antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse UBE3A
- Top Product
- Discover our top product ube3a Primary Antibody
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- 应用备注
- IHC/IF (H,M,R) 1:100-1:500/1:500-1:1300
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
- 别名
- UBE3A (ube3a 产品)
- 背景
- UBE3A (ubiquitin-protein ligase E3A, AKA E6AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Additionally, UBE3A may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins.
- 基因ID
- 22215
- NCBI登录号
- NP_035798
- UniProt
- O08759
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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