TMEM199 抗体
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北京 101111
Quick Overview for TMEM199 抗体 (ABIN7075998)
抗原
适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse TMEM199
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应用备注
- WB (H,M,R) 1:2000-1:4000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- TMEM199 (Transmembrane Protein 199 (TMEM199))
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别名
- TMEM199
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背景
- TMEM199, also named as C17orf32, is a component of the complex sense antisense architecture (CSAGA).Accessory component of the proton-transporting vacuolar (V)-ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation . May be involved in Golgi homeostasis.
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分子量
- 23 kDa
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基因ID
- 195040
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NCBI登录号
- NP_954669
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UniProt
- Q5SYH2
抗原
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