TEX264 抗体
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- 抗原 See all TEX264 products
- TEX264 (Testis Expressed 264 (TEX264))
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TEX264 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse TEX264
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- 应用备注
- WB (M,R) 1:1000-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- TEX264 (Testis Expressed 264 (TEX264))
- 别名
- TEX264 (TEX264 产品)
- 别名
- ZSIG11 antibody, TEG-264 antibody, testis expressed 264 antibody, testis expressed gene 264 antibody, TEX264 antibody, Tex264 antibody
- 背景
- Major reticulophagy (also called ER-phagy) receptor that acts independently of other candidate reticulophagy receptors to remodel subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover. The ATG8-containing isolation membrane (IM) cradles a tubular segment of TEX264-positive ER near a three-way junction, allowing the formation of a synapse of 2 juxtaposed membranes with trans interaction between the TEX264 and ATG8 proteins. Expansion of the IM would extend the capture of ER, possibly through a 'zipper-like' process involving continued trans TEX264-ATG8 interactions, until poorly understood mechanisms lead to the fission of relevant membranes and, ultimately, autophagosomal membrane closure.
- 分子量
- 34 kDa
- UniProt
- Q99LS5
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