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SIN3A 抗体

SIN3A 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7075609
发货至: 中国
  • 抗原 See all SIN3A 抗体
    SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
    适用
    • 42
    • 41
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 53
    • 2
    • 1
    克隆类型
    • 44
    • 12
    多克隆
    标记
    • 28
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SIN3A antibody is un-conjugated
    应用范围
    • 37
    • 22
    • 10
    • 9
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse mSin3A
  • 应用备注
    IHC/IF (M,R) 1:100-1:200/1:100-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    SIN3A (SIN3 homolog A, transcription regulator (SIN3A))
    别名
    mSin3A (SIN3A 产品)
    背景
    The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. And It acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.
    基因ID
    20466
    NCBI登录号
    NP_001103820
    UniProt
    Q60520
    途径
    Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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