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- 抗原 See all RANGRF 抗体
- RANGRF (RAN Guanine Nucleotide Release Factor (RANGRF))
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RANGRF antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse MOG
- Top Product
- Discover our top product RANGRF Primary Antibody
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anti-RAN Guanine Nucleotide Release Factor (RANGRF) (AA 1-146) antibody
RANGRF 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H4 unconjugated
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- 应用备注
- IHC/IF (M,R) 1:1000-1:3000/1:500-1:1500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- RANGRF (RAN Guanine Nucleotide Release Factor (RANGRF))
- 别名
- MOG1 (RANGRF 产品)
- 别名
- RGD1563195 antibody, mog1 antibody, rangnrf antibody, RANGRF antibody, zmynd19 antibody, DDBDRAFT_0186722 antibody, DDBDRAFT_0237751 antibody, DDB_0186722 antibody, DDB_0237751 antibody, HSPC236 antibody, MOG1 antibody, RANGNRF antibody, 2400006H24Rik antibody, Mog1 antibody, Rangnrf antibody, RAN guanine nucleotide release factor antibody, RAN guanine nucleotide release factor L homeolog antibody, Mog1 family protein antibody, Rangrf antibody, rangrf.L antibody, RANGRF antibody, rangrf antibody, DDB_G0285871 antibody
- 背景
- This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1. Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics (By similarity). Enhances the expression of SCN5A at the cell membrane in cardiomyocytes.
- 基因ID
- 57785
- NCBI登录号
- NP_001272370
- UniProt
- Q9JIB0
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