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P2RY12 抗体

P2RY12 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7075321
发货至: 中国
  • 抗原 See all P2RY12 抗体
    P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
    适用
    • 39
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    小鼠, 大鼠
    宿主
    • 41
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    克隆类型
    • 40
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    多克隆
    标记
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    This P2RY12 antibody is un-conjugated
    应用范围
    • 32
    • 13
    • 12
    • 6
    • 6
    • 5
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    • 3
    • 3
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    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse P2Y12
    Top Product
    Discover our top product P2RY12 Primary Antibody
  • 应用备注
    WB (M,R) 1:250-1:500, IHC/IF (M,R) 1:1000-1:3000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    P2RY12 (Purinergic Receptor P2Y, G-Protein Coupled, 12 (P2RY12))
    别名
    P2Y12 (P2RY12 产品)
    别名
    2900079B22Rik antibody, 4921504D23Rik antibody, P2Y12 antibody, ADPG-R antibody, BDPLT8 antibody, HORK3 antibody, P2T(AC) antibody, P2Y(12)R antibody, P2Y(AC) antibody, P2Y(ADP) antibody, P2Y(cyc) antibody, SP1999 antibody, P2y12 antibody, purinergic receptor P2Y, G-protein coupled 12 antibody, purinergic receptor P2Y12 antibody, P2ry12 antibody, P2RY12 antibody
    背景
    The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. Human platelets express two G protein-coupled nucleotide receptors, P2Y1 and P2Y12. P2Y12 is a receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. P2Y12 is an integral membrane protein involved in platelet aggregation. It is highly expressed in platelets, with lower levels in the brain, lung, appendix, pituitary and adrenal gland.
    分子量
    50 kDa
    基因ID
    70839
    NCBI登录号
    NP_081847
    UniProt
    Q9CPV9
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