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NLRP1 抗体

NLRP1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074850
发货至: 中国
  • 抗原 See all NLRP1 抗体
    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
    适用
    • 44
    • 18
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 41
    • 2
    • 1
    克隆类型
    • 44
    多克隆
    标记
    • 17
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRP1 antibody is un-conjugated
    应用范围
    • 30
    • 13
    • 13
    • 11
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse NLRP1
    Top Product
    Discover our top product NLRP1 Primary Antibody
  • 应用备注
    IHC/IF (M,R) 1:500-1:2000/1:250-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
    别名
    NLRP1 (NLRP1 产品)
    别名
    CARD7 antibody, CIDED antibody, CLR17.1 antibody, DEFCAP antibody, DEFCAP-L/S antibody, NAC antibody, NALP1 antibody, PP1044 antibody, SLEV1 antibody, VAMAS1 antibody, NLR family pyrin domain containing 1 antibody, NLRP1 antibody, Nlrp1 antibody
    背景
    NACHT, LRR and PYD domains-containing protein 1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. The NLRP1 protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
    基因ID
    195046
    NCBI登录号
    NP_001004142
    UniProt
    Q2LKU9
    途径
    Positive Regulation of Endopeptidase Activity, Inflammasome
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