电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Myosin Binding Subunit 抗体

MBS 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074731
发货至: 中国
  • 抗原 See all Myosin Binding Subunit (MBS) products
    Myosin Binding Subunit (MBS)
    适用
    人, 小鼠, 大鼠
    宿主
    • 1
    克隆类型
    • 1
    多克隆
    标记
    • 1
    This Myosin Binding Subunit antibody is un-conjugated
    应用范围
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    人, 大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse Myosin Phosphatase
  • 应用备注
    WB (H,M,R) 1: 500-1: 1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    Myosin Binding Subunit (MBS)
    别名
    Myosin Phosphatase (MBS 产品)
    背景
    Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase.
    分子量
    130 kDa
    基因ID
    17931
    NCBI登录号
    NP_082168
    UniProt
    Q9DBR7
You are here:
客服