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GDF15 抗体 (AA 221-308)

Name: GDF15 抗体 (AA 221-308)
SKU: ABIN704561
Availability: OutOfStock

GDF15 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Lane 1: Human K562 lysates, Lane 2: Human A431 lysates probed with Rabbit Anti-GDF15/MIC-1 Polyclonal Antibody, Unconjugated at 1:5000 for 90 min at 37˚C. (GDF15 抗体 (AA 221-308))

Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti--GDF15/MIC-1 Polyclonal Antibody, Unconjugated (ABIN704561) at 1:200, followed by conjugation to the secondary antibody and DAB staining (GDF15 抗体 (AA 221-308))

IHC

2 images

(4 references)

产品编号 ABIN704561

发货至: 中国

Datasheet as PDF

抗原 See all GDF15 抗体

GDF15 (Growth Differentiation Factor 15 (GDF15))
抗原表位
17

14

11

8

7

5

5

5

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 221-308
适用
94

27

20

1

1
人, 小鼠, 大鼠
宿主
88

13

3

1
兔
Compatible Secondaries
克隆类型
89

15

1
多克隆
标记
50

14

10

8

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This GDF15 antibody is un-conjugated
应用范围
84

52

37

18

12

12

7

7

6

5

5

2

2

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human GDF-15

亚型

IgG

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anti-Growth Differentiation Factor 15 (GDF15) (AA 16-143) antibody
GDF15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Growth Differentiation Factor 15 (GDF15) (N-Term) antibody
GDF15 适用: 人 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Ueno, Samura, Nakamura, Tanaka, Takeuchi, Kawamura, Takahashi, Hosoyama, Morikage, Hamano: "Increased plasma VEGF levels following ischemic preconditioning are associated with downregulation of miRNA-762 and miR-3072-5p." in: Scientific reports, Vol. 6, pp. 36758, (2016) (PubMed).

Ruan, Li, Nie, Zhou, Zou: "Differential expression of glycoprotein non-metastatic melanoma protein B (GPNMB) involved in trichostatin A-induced apoptosis in gastric cancer." in: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 4857-66, (2015) (PubMed).

Figueiredo, Aikawa, Zheng, Aaron, Lax, Libby, de Lima Filho, Gruener, Fingerle, Haap, Hartmann, Aikawa: "Selective Cathepsin S Inhibition Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice with Chronic Renal Disease." in: The American journal of pathology, (2015) (PubMed).

Li, Cui, Gao, Cao, Li, Zhou: "Downregulation of growth differentiation factor-15 in trichostatin A-induced apoptosis could play a role in progression of gastric cancer." in: International journal of clinical and experimental pathology, Vol. 8, Issue 7, pp. 8136-42, (2015) (PubMed).
抗原

GDF15 (Growth Differentiation Factor 15 (GDF15))

别名

GDF15/MIC-1 (GDF15 产品)

别名

GDF15 antibody, GDF-15 antibody, MIC-1 antibody, MIC1 antibody, NAG-1 antibody, PDF antibody, PLAB antibody, PTGFB antibody, SBF antibody, growth differentiation factor 15 antibody, GDF15 antibody, Gdf15 antibody

背景

Synonyms: PDF, MIC1, PLAB, MIC-1, NAG-1, PTGFB, GDF-15, Growth/differentiation factor 15, Macrophage inhibitory cytokine 1, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morphogenetic protein, Prostate differentiation factor, GDF15
Background: Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues.GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.

基因ID

9518

UniProt

Q99988

途径

SARS-CoV-2 Protein Interactome